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Antitrust Laws: Federal laws including Sherman Antitrust Act, Clayton Act, and Federal Trade Commission Act that prevent monopolies and ensure fair competition. These must be considered to ensure the exclusivity agreement doesn't illegally restrain trade.

Contract Law: State-specific contract laws, Uniform Commercial Code (if applicable to goods), and common law principles governing contract formation, enforcement, and interpretation.

Restraint of Trade Principles: Legal principles governing the reasonableness of restrictions, including geographic scope limitations, duration limitations, and scope of exclusive rights granted in the agreement.

Industry-Specific Regulations: Relevant federal or state regulations specific to the industry in which the agreement operates, including any applicable licensing requirements or regulatory compliance obligations.

Intellectual Property Laws: Federal laws including Patent Act, Trademark Act (Lanham Act), Copyright Act, and Defend Trade Secrets Act that protect and govern intellectual property rights within the exclusive relationship.

State-Specific Requirements: State-level legal requirements including blue pencil doctrine, specific enforcement rules, and public policy considerations that may affect the agreement's enforceability.

International Law: If applicable, international trade agreements, foreign competition laws, and export/import regulations that may impact cross-border aspects of the exclusive relationship.